Abstract: Establishing a reliable bidirectional communication interface between the nervous system and electronic devices is critical for exploiting the full potential of neurotechnology. Despite recent advancements, current technologies evidence important shortcomings, e.g. lack of focal stimulation, low signal-to-noise ratio, etc. Thus, efforts to explore novel materials are essential for the development of next-generation neural interfaces. Graphene and graphene-based materials possess a very attractive set of physicochemical properties holding great potential for implantable neural interfaces.
This presentation provides an overview on the technology and applications of graphene-based thin film devices for neural stimulation and recording. It covers device architectures, microfabrication, and surface engineering for improved charge injection and noise reduction. Furthermore, this contribution summarizes in vivo performance, including spatial selectivity, chronic stability, in rodent and large-animal models. Finally, the talk will address recent efforts toward clinical translation of this technology, including topics like scalable manufacturing, safety, and regulatory testing.
Bio: Jose A. Garrido is an ICREA Research Professor at the Catalan Institute of Nanoscience and Nanotechnology (ICN2) in Barcelona, where he leads the Advanced Electronic Materials and Devices group. He received his Master’s and PhD degrees in Telecommunication Engineering from the Polytechnic University of Madrid, and a habilitation degree from the Technical University of Munich. Since 2017 he has served as ICN2’s Vice-director, contributing to its scientific and innovation strategy. His research focuses on the science and technology of 2D materials and their application in bioelectronics and neural interfaces. He leads major national and European research initiatives aimed at developing novel neural interfaces for biomedical applications. He is also co-founder and Chief Scientific Officer of INBRAIN Neuroelectronics, an ICN2 spin-off company developing graphene-based neural devices for medical applications.